Out of the box there is nothing to do - just start the virtual machine and connect to the application URL (the machines IP address), done!
If you would like to configure the virtual machine to use HTTPS, static IP address or set the hostname or set the IP options security to your liking, see here - Getting Started, Configuring the Appliance. By default the virtual machine will get it's IP address from DHCP.
Start the virtual machine and configure the simply use a browser to connect to the IP address of your virtual machine.
From here either click the "Simple Configuration Wizard" icon or check out a particular Module by clicking it's icon. For more on configuring application settings, see here - Getting Started, Configuring the Applications